It was banned by the food and drug administration fda in 1991. Citrullus colocynthis 2 growth its fruit, which is lemonsized, yellowish, greenmottled, spongy, and extremely bitter, is a powerful hepatic stimulant and hydragogue cathartic. Citrullus colocynthis contained carbohydrate, protein, separated amino acid, tannins, saponins. Colocynth, citrullus colocynthis, hairystemmed perennial vine of the gourd family cucurbitaceae, native to the mediterranean region. Citrullus colocynthis is used to treat diabetes, since it may be able to induce insulin secretion from the pancreas after supplementation, while reducing blood glucose and improving lipid levels. Anticandidal screening and antibacterial of citrullus. Sekar abstract phytochemical screening of citrullus colocynthis belonging to the family cucurbitaceae was carried out for finding its medicinal values. C have been used traditionally in the treatment of diabetes mellitus. Synonym cucumis colocynthis, citrullus colocynthis l. Colocynth citrullus colocynthis uses, dosage, side effects. Medicinal action and usesit is a powerful drastic hydragogue cathartic producing, when given in large doses, violent griping with, sometimes, bloody discharges and dangerous inflammation of the bowels. We, for the first time, conducted this quantitative study in the area to document medicinal plants uses, to preserve traditional knowledge, and also to motivate the local residents against the vanishing wealth of traditional knowledge of medicinal flora.
Citrullus colocynthis, a member of the cucurbitaceae family, is widely distributed in north africa. Representation of different chemical constituents found in various plant parts extracts of citrullus colocynthis l. This study was carried out in human breast cancer cell growth. The current work investigates the effects of pulp and seed extract of c. Phytochemical analysis of a folklore medicinal plant citrullus colocynthis l bitter apple c. These pains may be accompanied by a backache and may even cause some sort of numbness at certain points. Bitter apple herb uses, benefits, cures, side effects, nutrients. Medicinal uses of different parts of citrullus colocynthis. Citrullus colocynthis is used to treat diabetes, since it may be able to induce insulin secretion from the pancreas after supplementation, while. Egusi seed is botanically known as citrullus colocynthis curcurbita citrullus l. Herbal medicinal importance of citrullus lanatus mentioned in the ahadith. Uses dried pulp of unripe fruit is used medicinally for its drastic purgative and hydragogue cathartic action on the intestinal tract. Jan 15, 2018 colocynth indravaruni, bitter apple is a great herbal plant with many useful properties.
Jun 14, 2018 citrullus colocynthis, also known as bitter cucumber, is a fruitbearing plant sometimes used medicinally citrullus colocynthis is used to treat diabetes, since it may be able to induce insulin secretion from the pancreas after supplementation, while reducing blood glucose and improving lipid levels. The colocynth grows in sandy, coastal, or desert soils and commonly spreads vegetatively. Citrullus colocynthis at encyclopedia of life citrullus colocynthis at national center for biotechnology information. Colocynthishomaccord injection solution is a clear, colorless solution. Phenolic compounds and antiradical properties of methanolic. The present study reveals the medicinal uses, chemical compositions and examines recent investigations on the therapeutic activities of extracts and chemicals identified from citrullus colocynthis. Issn phytochemical analysis of a folklore medicinal plant. The article also presents some of the functions of the chemicals present and attempt to emphasize and create an awareness of the great potential of citrullus colocynthis as a source of novel. Citrullus colocynthis, an israeli desert plant, as a. Introduction the use of plants for medicinal purposes has been.
Four patients with colocynth intoxication are presented. Citrullus colocynthis bitter apple ayurvedic properties. A qualitative analysis was performed for the identification of. The present study aimed to investigate the antiobesity effect. Thisisalsousedforthepoisonoussoda apple,aspeciesofnightshade. This is a dangerously powerful plant that has been found to work as a medicine in ayurveda as well as homeopathy. The present study aimed to investigate the antiobesity effect of the ethanol extract of colocynth flesh fcee in 3t3l1 cells following treatment at different doses. However therapeutic applications and adverse effects of c. Medicinal the dried, unripe fruit pulp constitutes the drug colocynth, which is a very strong laxative. Citrullus colocynthis famine foods plants that are not normally considered as crops are consumed in times of famine purdue university, west lafayette, indiana. The effect of pulp and seed extract of citrullus colocynthis. Citrullus colocynthis fruits were also traditionally used as an abortifacient and to treat constipation, oedema, bacterial infections, cancer and diabetes 47.
Chemical constituents and pharmacological effects of citrullus. Citrullus colocynthis fruits are usually recognized for its wide range of medicinal uses as well as pharmaceutical and nutraceutical potential. Medicinal action and uses it is a powerful drastic hydragogue cathartic producing, when given in large doses, violent griping with, sometimes, bloody discharges and dangerous inflammation of the bowels. Citrullus colocynthis is a medicinal plant that has anticancer property mediated by apoptosis. Colocynthis, bitter apple, bitter cucumber, colocynth. This powder is so inflammable that the arabs collect it to use as kindling. There have been reports of death following ingestion of just 112. The present study aimed to investigate the antiobesity effect of the ethanol extract of colocynth flesh fcee in 3t3l1. Citrullus colocynthis fruits are usually recognized for its wide received in revised form range of medicinal uses as well as pharmaceutical and nutraceutical. Citrullus colocynthis, with many common names including colocynth, bitter apple, bitter. Enhancement of callus induction and cucurbitacin content.
Phenolic compounds and antiradical properties of methanolic extracts of citrullus colocynthis and plantago major in iran afsaneh moslemi mehni 1, fatemeh shahdadi 2 1young researchers and elite club, jiroft branch, islamic azad university, jiroft, iran 2department of food engineering, jiroft university, iran key words. Colocynth citrullus colocynthis flesh extract suppresses. Persons familiar with the common watermelon vine need no description of the plant which produces colocynth apples. The folk knowledge of medicinal plants species of kohesafaid range was unexplored. Enhancement of callus induction and cucurbitacin content in citrullus colocynthis l.
Citrullus colocynthis schrad, aqueous extract, acetone extract, antibacterial, anticandidal, iran. Origin native asia, mediteranean region, tropical africa. Effects of alkaloid rich extract of citrullus colocynthis fruits on artemia salina and human cancerous mcf7 and hepg2 cells aniruddha mukherjee, savita d patil abstract in the present research the anticancer effect of alkaloid rich extract of citrullus colocynthis fruits was investigated. Its botanical name is citrullus colocynthis and it belongs to cucurbitacae family. Quantitative study of medicinal plants used by the. Phenolic compounds and antiradical properties of methanolic extracts of citrullus colocynthis and plantago major in iran afsaneh moslemi mehni 1, fatemeh shahdadi 2 1young researchers and elite club, jiroft branch, islamic azad university, jiroft, iran 2department of. Citrulluscolocynthis bitterapple and spelling variants redirect here. Citrullus colocynthis is a very droughttolerant medicinal species, closely related to watermelon c. Colocynthis citrullus, but is now classified as citrullus colocynthis. Citrullus colocynthis famine foods purdue university. May 10, 2010 colocynthis works well for sharp pains down the outer side of the thigh, leg, or foot. Citrullus colocynthis, commonly known as the colocynth, bitter apple, bitter cucumber.
It was always known as a toxic gourd but was turned to as a food in desperate times. This plant tends to control kapha and pitta doshas. Citrullus colocynthis supplement health benefits, dosage. Citrullus colocynthis as the cause of acute rectorrhagia. We have found, for example, that remedies which come from the same family of plants all share a number of characteristics. A qualitative analysis was performed for the identification of the presence. Despite serious safety concerns, colocynth is used for diabetes, high cholesterol and blood fats called triglycerides, constipation, and tuberculosis. Other side effects include convulsions, paralysis, and death. Nov 19, 2017 citrullus colocynthis has a number of interesting names like indrayan hindi, bitter apple, vine of sodom, and desert gourd. Colocynthis tends to be the most beneficial as a homeopathic remedy for those who have suppressed anger. When the fruit is ripe its pulp dries to form a powder used as a bitter medicine and drastic purgative. Provided by ars systematic botany and mycology laboratory.
Dec 31, 2014 medicinal herbs such as citrullus colocynthis c. C and its natural variants are not determined well. Herbal medicinal importance of citrullus lanatus mentioned in. Bitter apple herb uses, benefits, cures, side effects. Chemical constituents and pharmacological effects of. An other medicinal use of this plant declared by herbal medicine. The second edition of an excellent guide to the edible uses of plants, though it does not give any details of cultivation etc. The fruits are recognized for their wide range of medicinal uses and promising pharmaceutical potential. It is known by various names such as bitter cucumber, pumpkin seeds, egusi melon, vine of sodom plant, wild gourd, bitter apple, colocynth or desert gourd.
Effects of alkaloid rich extract of citrullus colocynthis. Taking even very small amounts of colocynth can cause severe irritation of the stomach and intestine lining, bloody diarrhea, kidney damage, bloody urine, and inability to urinate. In order to document the traditional uses of citrullus colocynthis survey was carried out during the. How bitter apple is effective for various diseases is listed in repertory format. Citrullus colocynthis 2 growth its fruit, which is lemonsized, yellowish, greenmottled, spongy, and extremely bitter, is a. There have been reports of death following ingestion of just. Jonathan hardy discusses two patients treated with medicines in the cucumber family in recent years we have developed our homeopathic understanding of remedies in groups and families.
Citrullus colocynthis has a number of interesting names like indrayan hindi, bitter apple, vine of sodom, and desert gourd. The folk medicinal use as a broadspectrum antimicrobial agent is validated. Journal of medicinal plants studies ethnobotanical studies of. The seeds of colocynth, which must be heated to remove their bitter bioactive. Schrad is a valuable cucurbit plant, widely distributed in the desert areas of the world.
It was known in biblical times as a source of seed oil and its fruits were used as an efficient laxative. Pdf medicinal utility of melon citrullus colocynthis l. Colocynth indravaruni, bitter apple is a great herbal plant with many useful properties. Uses, benefits, cures, side effects, nutrients in bitter apple. Citrullus colocynthis, also known as bitter cucumber, is a fruitbearing plant sometimes used medicinally. Colocynthis homaccord fda prescribing information, side. Indeed, if you will imagine a watermelon vine bearing a small, hard fruit with a bitter pulp, you. Enhancement of callus induction and cucurbitacin content in. Citrullus colocynthis on integrated taxonomic information system. Colocynth is used on the skin for nerve pain in people with diabetes. Report by journal of the alabama academy of science.
Names of bitter apple in various languages of the world are also given. Current situation of micronutrient deficiencies in west africa pdf. The main clinical feature was acute rectorrhagia preceeded by mucosal diarrhea with tenesmus, which gradually progressed to bloody diarrhea and overt rectorrhagia within 3 to 4 hours. Citrullus colocynthis an overview sciencedirect topics. Based on the above findings, the researchers agreed that citrullus colocynthis is suitable for use as an antiinflammatory agent. Citrullus colocynthis, with many common names including colocynth, bitter apple, bitter cucumber, desert gourd, citation needed egusi, vine of sodom, or wild gourd, is a desert viny plant native to the mediterranean basin and asia, especially turkey especially in regions such as izmir, and nubia. Pdf the present study reveals the medicinal uses, chemical compositions and examines recent investigations on the therapeutic activities of. The plant has small, pale greenish yellow flowers, forked tendrils, and. Science and technology, general agricultural chemicals antimitotic agents antineoplastic agents fertilizers research food additives germination liquid chromatography phytochemicals plant. Death has resulted from a dose of 1 12 teaspoonsful of the powder. The benefits, dosage and side effects of citrullus colocynthis. Herbal medicinal importance of citrullus lanatus mentioned.
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